ProTools Crackle, Audio Time Slower

[madams]

I have a random crackle sound and the speed of the audio output also slows down, physically hear it and set a timer measuring almost 2 seconds less in one minute. This happens when playing a single imported audio track through the mbox 2 connected over usb whether recording, number of tracks active, etc. It might start immediately from playback or after a minute or two or just random. I have read through a lot of threads but have not found anything that permanently helps. I have found that changing the number of processors, buffer size and cpu percentage do affect it. I can open the playback selection change the setting, even change it back to the setting which seams to work best while the window is open and select it and it'll work for a while. Maybe a few times of partial playback but not permanent.

New laptop, Toshiba/i7-6700HQ/4core/2.6GHz/8G RAM/Windows 10 (ProTools 10.3.8 & 11.3.1) and the cpu is not being used up at all. Tried 7 processors but that seems to crackle almost immediately from playback. Settled in at 4 processors, 1024/512 buffer size and around 80-90% cpu. THis lasts the longest but maybe only a couple times a 4 minute song has played all the way through. Version 10 & 11 have same problem. Did also notice at first in 10, the mix window would not actively show the power meter while playing unless the mix window was selected. Don't know how but that went away and now even if the track window is highlighted, the power meters in the mixer window are active real time. Also, a new dell i5-6200U of my wife's crackles the same but didn't spend a lot of time to tell if it was as much or not.

FYI: Other desktop system is an AMD FX-8320/8G RAM/Win 10/ same software and I've never had a crackle sound or problems.

Question of IRQs: Only Elan SMBus drive and High Definition Audio controller both have same IRQ. Disabled audio controller,(taking out normal sound) but didn't change crackle problem. Would this still matter?

Hard Drive in laptop is 5400rpm/1TB but SATA 6Gbps(HTS541010A9E680) so don't know if it's slower than desktop which has a 7200rpm/320GB ATA(ST3320613AS)?

Latest 6th generation i7 processors or windows 10 compatibility problem?

Mbox 2 driver is "Mbox 2 USB Family Drivers v9.0.2.65" Last update and only one I found to work.

Haven't spent time to see if 1 processor selected would work, would defeat purpose of i7....

Not sure but will look into disabling USB power management.

Graphics, what do I look at?