Best OS for MBP 2016 / Scarlett 4i4 / ProTools

[Mogwok]

Hi, this is a pre-emptive OS question (not troubleshooting):

I am wondering if anyone has advice about what is the best OS to use on a 2016 MacBook for ProTools 12 with a Scarlett (4i4).

(Late 2016 MBP is 15 inch, 2.6 GHz Intel Core i7, 16 GB 2133 MHz LPDDR3, Intel Graphics 530 1536 MB)

I am upgrading from Sierra, and according to the documentation for both Scarlett and ProTools I can choose from Mohave 10.14.6, Catalina 10.15.7, or Big Sur 11.6 (all are compatible).

According to ProTools, there appear to be some known issues with Big Sur (namely, users may experience graphical issues when scrolling), so I think it's down to Mojave or Catalina.

If anyone has had any issues or luck with one or the other on the same or similar setup, I'd love to hear it!

My thought process is that the OS needs to be advanced enough for bug fixes / to not fall behind too quickly, but not so advanced my old computer can't 'keep up'.

I've had many, many compatibility issues and bugs in the past, so I'm trying to be extra thoughtful this time around. I do intend to follow the computer optimization protocol for any OS I choose.

Thank you!