[Darryl Ramm]

No disk will not be causing signal to 'fade out'. But before you mess around with anything do make sure you have your sessions safely backed up.

You are reporting several problems. They may or may not be related. Start at one end and pull on the string and see where that takes. Nobody here is likely to be able to guess what the problem is.

If guitar signals are fading out then try solving/checking for that.

Is the dry guitar signal getting to the preamp reliably? Guitar or cable or DI box or preamp problem? Start at one end and follow stuff though and try to reproduce the glitch. Do you mean drop out and not get recorded or do you mean drop out in the monitor...or both? And how are you monitoring that guitar signal? -- through an interface hardware monitor? Or Pro Tools or what? ... if if does not drop out during recording is that because you are motoring though hardware monitoring?

Latency can only be caused by plugins or IO buffer or some routing you are doing that takes a signal though multiple IO buffers or plugins, and maybe you are missing that routing. You are on Pro Tools 10 so you are not messing with split IO buffers which excludes some issues.

If what you changed recently to install a plugin uninstall it, or at least move it's .aaxplugin files out of the plugin folder. Just not using it won't necessarily prevent it from causing problems although latency is unlikely to be one. And trash prefs.

Make sure ignore errors is not checked as that increases the latency.

Start with an empty session and one mono audio track and record a signal and work out what the latency is...