[Postman]

I tried a Wacom (pronounced "wah-cum", emphasis on the "wah") tablet, and it worked fine. If I had to choose one over the other I would still stay with the mouse, but that is because I mix with a console. Keeping track of the pen was not a skill I developed. I think it would be more valid in other circumstances, and I really enjoyed drawing waveforms and other curves with it! I finally abandonded it because it cluttered my space more than it helped my wrist.

As far as the wrist problems, I've found that mouse shape makes a difference (I personally like Kensington). Strength exercises for wrist and fingers and attention to relaxed hand positions have helped me greatly. Frequent breaks to change hand positions for a few moments help, and don't necessarily stop the work flow. One of the reasons I like keyboard shortcuts is because they reduce mouse dependency and these kinds of problems.

Good luck, and definitely address the problems now, while you can reverse any possible consequences!