I'm using HD Native Thunderbolt with an Omni and 192 on a 2019 MacBook Pro i9, running hybrid with outboard gear. Works great. One thing to note is that HD Native doesn't support sleep. So be careful with closing your laptop or putting it to sleep with HD Native connected. I generally work in clamshell mode with an external monitor, and I have sleep set to never, so not a problem for me. Another thing that helped me, although not related to Pro Tools or HD Native specifically, is that the fans in the MacBook can get really loud really fast. So I use Turbo Boost Switcher to turn off Turbo Boost (overclocking). This has DRAMATICALLY reduced fan noise on my system.
http://tbswitcher.rugarciap.com