Re: reopened session sounds different
I have had the abovementioned two issues with my Intel system as well (7.3.1cs4 on MacPro, 10.4.9).
I've had hard pans revert to center, and every now and then a DSP shuffle will cause an aux track or a TDM plugin on an aux track to stop passing signal, or pass signal at a greatly reduced level. If you can figure out what stopped working, disabling and re-enabling the plugin/aux will get it working again. Of course this is a little scary if it's a busy mix where you might not notice it right away....
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