You should download and install the cs2 update:
kb362855
Quote:
Fixed: Kernel Panic when shutting down Mac if Mbox 2 was disconnected previously (Item #56617)
Mac computers would kernel panic (crash) on shut down if the computer was started with an Mbox 2 USB device (Mbox 2, Mbox 2 Mini, or Mbox 2 Micro) attached, and the Mbox 2 is disconnected prior to shutdown.
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