[JFreak]

First of all, changing outputs during playback is not a good idea if you have delay compensation on (and why would it be off). This has nothing to do with sampling rates or clocking per se, but a change in delay compensation always forces a reset to everything which is why you should do it with playback stopped.

Now if changing outputs during playback is essential to your workflow, you should turn off delay compensation and basically have all-avid interfaces which is a known quantity. Avid is not testing third party boxes.