Pro Tools 12 No Playback or Record

[tangoportland]

Hello PT Community....PT 12.4 was working but not now.
When I have the focusrite 2i2 plugged in it will not playback a previosly recorded session. When I record enable a track PT quits and shuts down.
When I have the FR unplugged from my computer the session playsback.

Is it a windows playback setting or i/o setting in PT?
Usually it works fine.
I tried making a new session and same problem.

Thanks

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Microsoft Windows 7 Ultimate 6.01.7601
< Processor >
Manufacturer: Intel
Model: Intel(R) Core(TM) i5-2500K CPU @ 3.30GHz

< Logical Storage Devices >
System Reserved (E:): 100MB (NTFS) @ WDC WD5002AALX-00J37A0
(500.1GB, SATA600, 3.5", 7200rpm, 32MB Cache)
New Volume (C:): 168GB (NTFS) @ INTEL SSDSC2BW180A3H (180GB,
SATA600, 2.5", SSD)
WD HD (F:): 466GB (NTFS) @ WDC WD5002AALX-00J37A0
(500.1GB, SATA600, 3.5", 7200rpm, 32MB Cache)