Protools could not initialize audio driver

[def3mno62]

Whenever I try click the play button I get this message: "Protools could not initialize the Focusrite USB 2.0 audio driver. Please make sure that the device has been configured correctly." I've had this problem way in the past when I first got protools and can't remember how I fixed it. It was working perfectly fine before and just randomly I get this message :/ I tryed pressing N at the splash screen and changing it to all the different options but that either didn't change anything or I'd just get a different error message in its place so help would be appreciated