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Since ProTools requires M-Audio hardware, the question is would ProTools still work if remove Profire 610 and connect only Axiom Pro 61 to Alesis MasterControl which is then connected to PC via Firewire?
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Pro Tools M-Powered would still require a qualified audio interface (such as the ProFire 610) from the list on that page you linked to. The Axiom Pro is a keyboard controller, not an audio interface, and would not allow Pro Tools M-Powered to launch without having the ProFire also connected to the computer running Pro Tools M-Powered.