[j20056]

I use BFD2 with the Andy Johns and the Joe Barresi samples, and it works fine. Setup is 8-core MacPro, Digi 002R and PT 8.0.3 on OS10.5.8 with 8gb RAM and 4 internal HDs, plus teo external 2TB for backup via Time Machine.
Until I allocated 8-1=7 cores, I was having immense problems, and even switched to Logic 8 for a while. It just wasn't the same, athough pretty good actually. When PT8 came out, I felt compelled to upgrade, and I've been happy since. I can run simultaneously BFD2 + Smapletank 2.5 + Guitar Rig 3 (multiple instances) all that at 64 samples, which mostly eliminates the latency.
System + PT on Drive 1, samples on Drive 2 and audio files + bouncing on Drive 3. Not sure you need the 4th drive. I use it for video editing instead.
Although Digi recommends to not run anything else, I can run the Apple iLife09 software, Photoshop, and even iTunes at the same time as PT, and it all works actually. I get the system and iTunes audio out from the lightpipe into a digital mixer, it doesn't use my 002R.