Which version of OSX are you running?
Have you done all of the recommended optimizations for PT 12 on Mac?
System Optimization Guides
AAE -6101 has been an issue with systems with integrated video cards. Not much you can do on a Mac Book, so I would make sure you go through your system settings and make sure things like App Nap are off, power settings are set to recommended settings.....
Also, how much memory does your system have? An integrated video card uses system memory.