[Drew Mazurek]

I'm going to ask the obvious question.... why?

What do you hope to achieve doing this? If you think you'll be imparting any sort of analog "mojo" with the Mackie, I think you'll be disappointed.

If you need a clean mixer to blend mics together on their way to the DAW (a dubious endeavor these days) because your interface only has so many inputs, I suppose this would work, but I'd simply recommend you get another interface and not mess around with this.