Yes, the 003 should work fine right up to version 12(assuming a compatible computer and firewire controller). Since version 9, its the iLok license that tells Pro Tools to open as HD or non-HD
(and HD will also work with the 003 but minus the TDM processing). As for tracking latency, with careful selection of plugins, a modern computer that is properly tweaked, you should have no trouble tracking all the available inputs of the 003 and 24-30 tracks at the 64 buffer. That buffer and no active plugins with more than 10 samples of latency and the vast majority of players will be fine with the latency over firewire(I tracked many a band with a DIGI003, running all 18 inputs for a few years before moving up