If the instrumental an exact duplicate minus vocals (and most of the time it's not unless you did this yourself, but then you wouldn't be asking how to do this lol) you could try flipping the phase of the instrumental track and see what happens. I wouldn't hold my breathe.
There are some plugs that can adjust the width and balance of the the center vs the L/R, but those won't completely remove anything. Also there are probably other instruments panned center that would still be there.
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Dell T5810. Harrison Mixbus 32C. Haven't used PT since 2015 and never been happier. 
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