[nst7]

You can have up to 64 in and 64 out on an HD Native card (or Thunderbolt unit). This can be done by using various HD interfaces like the HD IO (16x16, 8x8, or digital), or the older blue interfaces like the 192 or 96io. Or you can use 3rd party interfaces that hook up to HD cards, such as some of the Apogee units.