Well, it appears that the problems in my original post have returned... Or, more likely, were never actually fixed.
I have discovered that they are happening on some projects, but not others.
Latest drivers for everything are installed.
This is driving me nuts. Any more insight from anyone?
PS - I still haven't attempted a graphics driver update on PC 1, but PC 2 is continuing to give me these issues even though it is fully up to date.