[BobbyDazzler]

I've just gone from a MacPro 5.1 to a HP.
The notable stuff for me has been that the PC was unusable before I began optimising. It wouldn't even reliably record 1 track for more than 5 minutes with no plugins.
I got it to 16 tracks each with 5 Reverb One plugs recording for an hour at a 128 buffer (48k). It still has it's weird days, but so did my MacPro.
I remapped my mac keyboard because I didn't feel like learning the PC equivalents.
I lost the use of Source Nexus (Mac Only), and Source Connect is a bit more involved (you need to make sure you have a Source Connect 3.8 license because there is no 3.9 for PC).
There is no ADR software for PC that I've found.
PC ProTools looks ugly.
I have been getting serious graphics glitches, and will submit a bug report when I get some screen shots.
I'll probably go back to Mac once the dust has settled with the migration away from Intel.