[Dizzi45Z]

I am running into this same issue as well. Pro Tools 2019.12.0.

This happened to me on 2019.6 as well. It only seems to happen to me in 96k sessions. It seems to primarily happen on Auxillary tracks for me and the plug-ins that seem to be possibly having the issues are Echoboy, RVerb, TL Space and even D-Verb. I've been troubleshooting over and over again and every time I reopen the session several plug-ins are inactive that were not inactive before. I can not figure out what is causing it.

Like the original post says, it happens on only some of the plug-ins, neighboring busses that have the same plug-ins on them will load just fine. You can simply make them active again and they work.

Very scary and irritating as I keep forgetting to make them active again and I've made bounces with some of the plug-ins inactive to send to be mastered and realized after the mixes are sent.

I'm on Mac OS 10.12.6 Mac Pro Mid 2012, 3.2 GHz Quad Core with 32 GB of RAM. Pro Tools HDX1