[YYR123]

Seems familiar but I can't remember exactly....I just spent the last 10 min searching the DUC but still can't place it.

I would say try these Troubleshooting steps first.

1. Change playback engine and record something from another interface.
2. Reconnect all relevant cards, connectors, "DSub" Cables and the like.
3. Change your computer and your interface power sources....even if you have to use an extension cord, just for checking purposes.